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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Optimization of culture conditions of human HepG2 liver cells on 4 types of nano- and micro-fiber carriers
 Rössner ml., Pavel
The technology describes the optimization of the number of deployed human hepatocytes HepG2, suitable for use in the field of toxicological verification of new drugs or foods, on a 3D culture system consisting of four types of nano- and microfiber carriers. The motivation for finding suitable models for testing potentially genotoxic effects of drugs is the low relevance of tissue models used in the first stages of preclinical evaluation of new substances, as well as the reduction of animal testing.
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A method for the use of nanofiber scaffolds and stem cells for the treatment of severe damages of the ocular surface
 Zajícová, Alena ; Javorková, Eliška ; Holáň, Vladimír
The method describes a new therapeutic approach for the treatment of severe ocular injuries in veterinary medicine. The protocol is based on a cultivation of stem cells and their transfer using nanofiber scaffolds onto damaged ocular surface. This method can be used in the cases when other available treatment options are not sufficient or cannot be used.
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